Plekhg6 Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comPlekhg6 Polyclonal Antibody for Mouse(Mus musculus)

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Plekhg6 (Gene name),

Pleckstrin homology domain-containing family G member 6 (Protein name ), PKHG6_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Plekhg6;

Protein name:

Pleckstrin homology domain-containing family G member 6(PH domain-containing family G member 6);

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with MYH10. Interacts with ELMO1 and EZR (in an open conformation).

Function:

Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.

Subcellular Location:

Cytoplasm Cytoplasm cytoskeleton spindle Cytoplasm cytoskeleton spindle pole Cleavage furrow During mitosis, localizes to the spindle pole, central spindle and cleavage furrow. In epithelial cells, recruited to the apical membrane by EZR.

Protein Attributes:

Sequence length:

787

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

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750:

787:

EPEPGNGKPR | RLTLAQLQRM | RVPHIIQLDT | PLSTSEV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q8R0J1

KEGG:

mmu:213522

UniGene:

Mm.333396

STRING:

10090.ENSMUSP00000037004

Pfam:

PF00621

String:

Q8R0J1

Uniprot:

Q8R0J1

FOR

ELISA Kit for Mouse PH domain-containing family G member 6

Cat.:

E4155h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Mouse PH domain-containing family G member 6

Cat.:

E4155m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse PH domain-containing family G member 6

Cat.:

U4155m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse PH domain-containing family G member 6

Cat.:

U4155h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse PH domain-containing family G member 6

Cat.:

P4155Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse PH domain-containing family G member 6

Cat.:

P4155Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse PH domain-containing family G member 6

Protein for Mouse PH domain-containing family G member 6

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Liver.

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